Author

Maren Schenke

Johns Hopkins UniversityORCID 0000-0001-5649-591XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Assay:electronic health records· 1

Frequent Co-Authors

Lena SmirnovaiD· 3 shared Dowlette‐Mary Alam El DiniD· 2 shared Jason LairdiD· 2 shared Tjitse van der MoleniD· 2 shared Aditya DendukuriiD· 1 shared Aidan L. Morson· 1 shared Alex Rittenhouse· 1 shared Alex SpaethiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Lena SmirnovaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 9, 2026

Encephalitic alphavirus infection reduces neurite outgrowth and downregulates Rho GTPase pathways in human iPSC-derived neurospheres

Karsten Cirksena, Lisa Maria Haiber, Britta Anna Kühne…·Gisa Gerold

DOI 10.64898/2026.10.08.755254

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 8, 2025

Genetic Background and Sex Modulate Androgen Responses in Human Brain Microphysiological System

Maren Schenke, Jason Laird, Alex Rittenhouse…·Lena Smirnova

This study shows that androgen responses in human brain organoids vary by genetic background and sex, affecting transcription, cell populations, and DNA methylation.

DOI 10.64898/2025.12.03.692130

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceNature NeurosciencePeer-reviewedNov 24, 2025

Protosequences in brain organoids model intrinsic brain states

Tjitse van der Molen, Alex Spaeth, Mattia Chini…·Tal Sharf

This study shows that structured firing sequences emerge in human and murine brain organoids and neonatal brain slices, suggesting innate rather than experience-dependent neural coding.

22 citationstop 1%

𝕏 PostBluesky

NeuroscienceCommunications BiologyPeer-reviewedAug 16, 2025

Human Neural Organoid Microphysiological Systems Show the Building Blocks Necessary for Basic Learning and Memory

Dowlette‐Mary Alam El Din, Leah S. Mönkemöller, Alon Loeffler…·Lena Smirnova

This study demonstrates that human neural organoids exhibit features of learning and memory by showing synaptic plasticity, criticality, and receptor expression.

28 citationstop 1%

𝕏 PostBluesky