Author

Raquel Cuella-Martin

McGill UniversityORCID 0000-0001-5682-5069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Tanja SackiD· 2 shared Abdul Hameed KhaniD· 1 shared Abdul Waheed· 1 shared Abrish Majeed· 1 shared Alberto CicciaiD· 1 shared Alejandro Álvarez-QuilóniD· 1 shared Amisha Minju-OP· 1 shared Ananya AcharyaiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

Tanja SackORCID

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 24, 2026

Anticipating on-target resistance to WRN inhibitors in microsatellite unstable cancers

Mark E. Orcholski, Nancy Laterreur, Wardah Masud…·Raquel Cuella-Martin

This study identifies on-target resistance mechanisms to WRN inhibitors in MSI cancers using functional genomics and shows how to improve therapeutic durability through drug selection and combination strategies.

2 citations

humanCRISPR screen

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Molecular BiologybioRxivPreprintOct 19, 2025

Divergent roles of DNA methylation, TRIM28, and p53 surveillance in human embryonic and trophoblast stem cells

Deepak Saini, Megan S. Katz, Skye Beck…·William A. Pastor

The paper investigates the roles of TRIM28, DNA methylation, and p53 in regulating gene and transposon expression in human embryonic and trophoblast stem cells, revealing divergent responses to genomic instability.

5 citations

humanDNA methylation

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Genetic & Genomic MedicinemedRxivPreprintJan 8, 2024

Rare splice and missense variants with evidence of pathogenicity in consanguineous families with autosomal recessive intellectual disability from Pakistan

Abdul Waheed, Robert J. M. Eveleigh, Danielle S. Perley…·Daniel Taliun

DOI 10.1101/2024.01.08.23299914

humanwhole-genome sequencing

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GeneticsbioRxivPreprintSep 3, 2019

Identification of MCM8IP, an interactor of MCM8-9 and RPA1 that promotes homologous recombination and DNA synthesis in response to DNA damage

Jen‐Wei Huang, Angelo Taglialatela, Ananya Acharya…·Alberto Ciccia

This study identifies MCM8IP as a DNA repair factor that promotes homologous recombination and DNA synthesis in response to DNA damage by interacting with MCM8-9 and RPA1.

1 citation

humanexperimental assay

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