Jia Sun

OCellus: A Language-Model Framework for Single-Cell, Spatial, and Perturbation Biology with Natural-Language Reasoning

OCellus is a language model that addresses limitations in single-cell, spatial, and perturbation biology by integrating natural-language reasoning across multiple tasks.

An allosteric pocket in KV1.3 defines a distinct chemical space for immunomodulator design

The paper identifies a novel allosteric pocket in KV1.3 that enables selective immunomodulator design, revealing a non-contact selectivity mechanism through structural analysis and inhibitor development.

Dawn of segmented bilaterians unveiled by soft-bodied fossils in microbial pseudomorphs from the Basal Cambrian

This paper describes the discovery of segmented bilaterian fossils from the lowermost Cambrian, preserved as microbial pseudomorphs, indicating a significant diversification during the Ediacaran-Cambrian transition.

Ex vivo human airway epithelia modelling reveals specific alterations in lung and hematopoietic stem cell transplant recipients

The paper examines ex vivo airway epithelial cultures from transplant recipients to identify epithelial changes associated with bronchiolitis obliterans syndrome.

VrySure: A Multi-Task AI Scientific Fraud Detection Platform for Identifying Manipulated and AI-Generated Biomedical Research Images

VrySure is an AI platform that detects manipulated and AI-generated biomedical images using multiple modules, achieving higher accuracy in some tasks compared to existing tools.