Author

Nozomu Kawashima

Broad InstituteORCID 0000-0001-5700-4481Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:genome assembly· 1 Assay:proteomics· 1

Frequent Co-Authors

Anca Manuela HristodoriD· 1 shared Basheer BecerraiD· 1 shared Cameron Jones· 1 shared Daniel E. BaueriD· 1 shared Frank A. TedeschiiD· 1 shared Gao ZhouiD· 1 shared Gue‐Ho HwangiD· 1 shared Hrishikesh MehtaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Anca Manuela HristodorORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 8, 2026

Hog1/p38 and ZAKα drive Shwachman-Diamond syndrome and provide targets to improve cell growth

Nozomu Kawashima, Nehas Prasad, Frank A. Tedeschi…·Seth J. Corey

This study identifies Hog1/p38 and ZAKα as drivers of Shwachman-Diamond syndrome and shows their inhibition can restore cell growth in SDS models.

DOI 10.64898/2026.02.05.703873

humanproteomics

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Molecular BiologybioRxivPreprintJun 16, 2025

In cellulo DNA assembly for targeted genomic integration and rearrangement in human cells

Sébastien Levesque, Nozomu Kawashima, Gue‐Ho Hwang…·Daniel E. Bauer

This paper introduces a method for targeted genomic integration and rearrangement in human cells using CRISPR-targeted dual flap synthesis, enabling DNA sequence assembly without requiring double-stranded DNA donors or cell cycle progression.

4 citations

humanexperimental assay

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