Joseph B. Prescott

This paper introduces an Oxford Nanopore sequencing framework for hantavirus genome assembly and variant analysis, revealing defective viral genomes as a new feature of hantavirus populations.

The paper uses sequential CRISPR activation screens to identify genes sufficient for viral entry into cells, demonstrating effectiveness with Ebola and rabies viruses.

This study develops an amplification-free CRISPR-Cas13 assay for detecting zoonotic viruses and finds that multiple crRNAs improve sensitivity for some viruses but not others.

This study compares macrophage responses to Marburg and Sudan viruses in Egyptian rousette bats, revealing divergent interferon and cytokine storm signaling pathways.

This study uses metabolically purified human hepatocytes to show that Ebola and Lassa viruses have distinct effects on liver cells.