Author

Timothy Chai

Stanford UniversityORCID 0000-0001-6258-066XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Kyle M. LohiD· 3 shared Alana T. NguyeniD· 1 shared Alicia Wong· 1 shared Andrew H. ChangiD· 1 shared Brian C. Raftrey· 1 shared Daniel BernsteiniD· 1 shared Emily TrimmiD· 1 shared Gaetano D’AmatoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Kyle M. LohORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintMar 6, 2026

Elucidating genes sufficient for viral entry into cells through sequential genome-wide CRISPR activation screens

Timothy Chai, Alicia Wong, Qingqing Yin…·Kyle M. Loh

The paper uses sequential CRISPR activation screens to identify genes sufficient for viral entry into cells, demonstrating effectiveness with Ebola and rabies viruses.

DOI 10.64898/2026.03.06.710083

genetic perturbation / CRISPRdrug response / drug discovery

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 22, 2024

TMX1, a disulfide oxidoreductase, is necessary for T cell function through regulation of CD3zeta

Timothy Chai, Kyle M. Loh, Irving L. Weissman

This study identifies TMX1 as a critical regulator of T cell function by modulating CD3zeta stability and TCR signaling.

2 citations

humanproteomics

𝕏 PostBluesky

Developmental BiologyCirculation ResearchPeer-reviewedAug 12, 2021

Dach1 extends artery networks and protects against cardiac injury

Brian C. Raftrey, Ian M. Williams, Pamela E. Rios Coronado…·Kristy Red‐Horse

This study shows that overexpressing Dach1 in endothelial cells extends coronary arteries and improves heart function after myocardial infarction in mice.

50 citations

mousescRNA-seq

𝕏 PostBluesky