Author

Rajashree A. Deshpande

Howard Hughes Medical InstituteORCID 0000-0001-5728-716XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Tanya T. PaulliD· 3 shared Alberto Marín-GonzáleziD· 1 shared Amanda DayiD· 1 shared Ana Paola Cotrim· 1 shared André NussenzweigiD· 1 shared Elsa CalléniD· 1 shared Hannah K. BarnesiD· 1 shared Ilya J. FinkelsteiniD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Tanya T. PaullORCID

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3 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedSep 16, 2023

Genome-wide analysis of DNA-PK-bound MRN cleavage products supports a sequential model of DSB repair pathway choice

Rajashree A. Deshpande, Alberto Marín-González, Hannah K. Barnes…·Tanya T. Paull

26 citations

DNA methylationexperimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedFeb 12, 2020

ATM and PRDM9 Regulate SPO11-bound Recombination Intermediates During Meiosis

Jacob Paiano, Wei Wu, Shintaro Yamada…·André Nussenzweig

This study directly detects meiotic DSBs and resection in vertebrates using END-seq on mouse spermatocytes, identifying a novel recombination intermediate regulated by ATM and PRDM9.

121 citationstop 2%

mouseDNA methylation

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Molecular BiologyScience AdvancesPeer-reviewedJan 8, 2020

DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP

Rajashree A. Deshpande, Logan R. Myler, Michael M. Soniat…·Tanya T. Paull

This study shows DNA-PK promotes MRN and phosphorylated CtIP for efficient DNA end processing, facilitating the transition from non-homologous end joining to homologous recombination.

138 citationstop 1%

humanexperimental assay

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