Laura H. Tang

The paper identifies impaired T cell priming and KLF2-dependent quiescence in gastric cancer draining lymph nodes as mechanisms limiting immune responses.

The paper investigates how aging-dependent dysregulation of EXOSC2 affects cellular traits and finds that PPP2R5E, a PP2A phosphatase subunit, is a key target of EXOSC2, with this regulation maintained in stem cells and cancer.

This study shows that loss of Kmt2c/d promotes gastric cancer initiation and makes tumors sensitive to mTORC1 inhibitors and anti-PD1 immunotherapy.

This study identifies two proteomic subgroups of intrahepatic cholangiocarcinoma with distinct time-to-recurrence rates and biological processes.