Author
Aldo S. Bader
University of CambridgeORCID 0000-0001-5760-5113Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 36 mutual co-author links5 papers
Recent·Most cited
- GeneticsEMBO Molecular MedicinePeer-reviewed
Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay
Soren H. Hough, Satpal S. Jhujh, Samah W. Awwad…·Stephen P. Jackson
The paper identifies MAEA as a critical regulator of DNA repair and replication, with loss of function causing developmental delay and neurodevelopmental deficits.
2 citations - Cancer BiologyNature CommunicationsPeer-reviewed
WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2
Jordan Wilson, Jiayi Zhu, Vanesa Vinciauskaite…·Stephen P. Jackson
This study shows WEE1 inhibitors work better with mRNA translation defects by activating GCN2, and suggests ways to reduce off-target effects.
3 citations - Molecular BiologybioRxivPreprint
iMUT-seq: high-resolution mapping of DSB mutational landscapes reveals new insights into the mutagenic mechanisms of DSB repair
iMUT-seq maps DSB-induced mutations with high sensitivity and resolution, revealing HR's mutagenic role and its suppression of genomic rearrangements.
3 citations - Molecular BiologybioRxivPreprint
ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations
Coline Arnould, Vincent Rocher, Aldo S. Bader…·Gaëlle Legube
The paper identifies a novel chromatin compartment formed by ATM-dependent clustering of damaged TADs, which enhances DNA damage response but increases translocations.