Author
Jiayi Zhu
University of CambridgeORCID 0000-0001-7401-6468Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 27 mutual co-author links4 papers
Recent·Most cited
- Cancer BiologyNature CommunicationsPeer-reviewed
WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2
Jordan Wilson, Jiayi Zhu, Vanesa Vinciauskaite…·Stephen P. Jackson
This study shows WEE1 inhibitors work better with mRNA translation defects by activating GCN2, and suggests ways to reduce off-target effects.
3 citations - ImmunologyNature CommunicationsPeer-reviewed
Distinct Binding Modes of Inter-Spike Cross-Linking Suggest a Supplementary Mechanism for SARS-CoV-2 Antibody Neutralization
Xuanyu Nan, Yujie Li, Rui Zhang…·Yuhe Renee Yang
This study uses cryo-EM to show that the W328-6H2 antibody forms different structures with SARS and Omicron BA.1 spike proteins, revealing a supplementary neutralization mechanism beyond RBD-Fab binding.
11 citations - ImmunologybioRxivPreprint
Enhanced Antibody Response to the Conformational Non-RBD Region via DNA Prime-Protein Boost Elicits Broad Cross-Neutralization Against SARS-CoV-2 Variants
Yun-Fei Ma, Kun Chen, Bowen Xie…·Ye Liu
This study shows that DNA prime-protein boost elicits enhanced antibodies against non-RBD regions of SARS-CoV-2, improving cross-neutralization against variants in mice.
DOI 10.1101/2024.02.04.578544