Author

Hui Guo

National Institutes of HealthORCID 0000-0001-5889-0374Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Hui Guo4 papers · First Affiliated Hospital of Kunming Medical University

Biology Disciplines

Click to filter author papers

Bioinformatics· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:graph neural network· 1 Organism:human· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Catherine Z. CheniD· 2 shared Matthew D. HalliD· 2 shared Miao XuiD· 2 shared Min SheniD· 2 shared Alexey Zakharov· 1 shared Anton SimeonoviD· 1 shared Jacob S. RothiD· 1 shared Jonathan H. Shrimp· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Catherine Z. ChenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMay 22, 2025

Identification of antibody-drug conjugate payloads which are substrates of ATP-binding cassette drug efflux transporters

Jacob S. Roth, Hui Guo, Lu Chen…·Matthew D. Hall

This study identifies ADC payloads transported by ABC transporters, showing potential for drug resistance and suggesting payload selection to avoid this.

7 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioinformaticsJournal of Chemical Information and ModelingPeer-reviewedApr 11, 2022

A Graph Convolutional Network-based screening strategy for rapid identification of SARS-CoV-2 cell-entry inhibitors

Peng Gao, Miao Xu, Qi Zhang…·Min Shen

The paper develops a graph convolutional network to screen compounds for SARS-CoV-2 entry inhibitors, identifying 16 active compounds from 170,000 virtual candidates.

8 citations

deep learninggraph neural network

𝕏 PostBluesky

BioinformaticsbioRxivPreprintDec 28, 2020

Discovery of TMPRSS2 inhibitors from virtual screening

Xin Hu, Jonathan H. Shrimp, Hui Guo…·Min Shen

This study identifies novel TMPRSS2 inhibitors through virtual screening and experimental validation, offering potential drug candidates for COVID-19 treatment.

9 citations

humanstatistical model

𝕏 PostBluesky