Author

Min Shen

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:simulation· 1

Frequent Co-Authors

Anton SimeonoviD· 2 shared Matthew D. HalliD· 2 shared Paul ShinniD· 2 shared Ajit Jadhav· 1 shared Alexey Zakharov· 1 shared Catherine Z. CheniD· 1 shared Dorian M. Cheff· 1 shared Ekaterina Kuznetsova· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBioinformatics

Anton SimeonovORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Repurposing the Antiviral Agent Pibrentasvir: In Vitro Synergistic Effects in Combination with Different Azole Antifungal Agents

Sijie Liu, Jing Hu, Min Shen, Lu Ge, Hanmo Yang, Xinyi Tao, Heng Zhang, Yi Sun

This study evaluates the in vitro synergistic effects of pibrentasvir combined with azole antifungal agents against several fungal pathogens.

bioRxiv · Aug 3, 2026 · PreprintMicrobiology

Discovery of TMPRSS2 inhibitors from virtual screening

Xin Hu, Jonathan H. Shrimp, Hui Guo, Miao Xu, Catherine Z. Chen, Wei Zhu, Alexey Zakharov, Sankalp Jain, Paul Shinn, Anton Simeonov, Matthew D. Hall, Min Shen

This study identifies novel TMPRSS2 inhibitors through virtual screening and experimental validation, offering potential drug candidates for COVID-19 treatment.

bioRxiv · Dec 28, 2020 · PreprintBioinformatics

Small Molecule Inhibitors of the Human Histone Lysine Methyltransferase NSD2 / WHSC1 / MMSET Identified from a Quantitative High-Throughput Screen with Nucleosome Substrate

Nathan P. Coussens, Stephen C. Kales, Mark J. Henderson, Olivia W. Lee, Kurumi Y. Horiuchi, Yuren Wang, Qing Chen, Ekaterina Kuznetsova, Jianghong Wu, Dorian M. Cheff, Ken Chih-Chien Cheng, Paul Shinn, Kyle R. Brimacombe, Min Shen, Anton Simeonov, , Matthew D. Hall

This study identifies five small molecule inhibitors of NSD2 through high-throughput screening and validates their activity in cell-based assays.

bioRxiv · Oct 24, 2017 · PreprintCancer Biology