Miao Xu

This paper develops potent humanized nanobodies against SARS-CoV-2 spike protein, showing effectiveness against the Alpha variant and providing structural insights into their neutralization mechanism.

The paper develops a graph convolutional network to screen compounds for SARS-CoV-2 entry inhibitors, identifying 16 active compounds from 170,000 virtual candidates.

This study identifies novel TMPRSS2 inhibitors through virtual screening and experimental validation, offering potential drug candidates for COVID-19 treatment.

This study shows SARS-CoV-2 can infect brain cells and organoids derived from human induced pluripotent stem cells, leading to cell death and inflammation, and suggests using these models to study the virus's effects on the brain.

This study identifies virus- and strain-specific molecular signatures of ZIKV infection in human cortical neural progenitors, showing distinct impacts on DNA replication and apoptosis.