Elisabeth Sock

The neuronal fate determinants SOX4/11 control mitotic fidelity of adult hippocampal precursor cells

This study shows that SOX4/11 transcription factors are critical for mitotic fidelity in adult hippocampal precursor cells, with loss leading to mitotic defects and cell death.

The chloride cotransporter NKCC1 regulates self-renewal of hippocampal neural stem cells via the transcription factor Sox11

This study shows that NKCC1 regulates hippocampal neural stem cell self-renewal via Sox11, with reduced NKCC1 in aging promoting symmetric division and decreased neurogenesis.

scRNA-Sequencing uncovers a TCF-4-dependent transcription factor network regulating commissure development

The paper identifies a TCF-4-dependent transcription factor network regulating commissure development in mice using scRNA-seq and bioinformatic analysis.

Deciphering the Regulatory Landscape of γδ T Cell Development by Single-Cell RNA-Sequencing

This study uses single-cell RNA-sequencing to uncover the developmental trajectory of γδ T cells, identifying c-MAF as a key regulator of IL-17-producing γδ T cell differentiation.