Author

Par Bjorklund

Karolinska University HospitalORCID 0000-0001-5904-7768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam Majcher· 2 shared Elkhan YusifoviD· 2 shared Thorsten HornemanniD· 2 shared Alaa OthmaniD· 1 shared Aleš HolfeldiD· 1 shared Alina Zurcher· 1 shared Andreas J. HülsmeieriD· 1 shared Aneta Čináková· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

Adam Majcher

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 14, 2026

CYP4F2-mediated ω-hydroxylation of 1-deoxysphingolipids reveals a new hepatic detoxification pathway

Adam Majcher, Essa M. Saied, Zoltán Kutalik…·Thorsten Hornemann

This study identifies CYP4F2 as a key enzyme mediating ω-hydroxylation of 1-deoxySLs, revealing a new hepatic detoxification pathway that reduces their cytotoxicity.

DOI 10.64898/2026.05.11.724297

humanmetabolomics

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NeurosciencebioRxivPreprintApr 25, 2025

Metabolic Origins of Neurotoxic 1-deoxySphingolipids in Type 2 Diabetes

Adam Majcher, Par Bjorklund, Aleš Holfeld…·Thorsten Hornemann

This study identifies metabolic origins of neurotoxic 1-deoxySL in T2D through proteomics, lipidomics, and metabolomics analyses in human and rodent models.

1 citation

humanmouse

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