Author

Andreas J. Hülsmeier

University Hospital ZurichORCID 0000-0001-6987-8979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

Thorsten HornemanniD· 3 shared Christoph ArenziD· 2 shared Essa M. SaiediD· 2 shared Adam Majcher· 1 shared Alaa OthmaniD· 1 shared Anna KovilakathiD· 1 shared Arnold von EckardsteiniD· 1 shared Belle Vivica van RosmaleniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBiochemistry

Thorsten HornemannORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

CYP4F2-mediated ω-hydroxylation of 1-deoxysphingolipids reveals a new hepatic detoxification pathway

Adam Majcher, Essa M. Saied, Zoltán Kutalik, Maftuna Shamshiddinova, Andreas J. Hülsmeier, Par Bjorklund, Elkhan Yusifov, Irina Alecu, Christoph Arenz, Thorsten Hornemann

This study identifies CYP4F2 as a key enzyme mediating ω-hydroxylation of 1-deoxySLs, revealing a new hepatic detoxification pathway that reduces their cytotoxicity.

bioRxiv · May 14, 2026 · PreprintBiochemistry

Dyslipidemic SPTLC3 Integrates Bile Acid-FXR Signaling with Sphingolipid Remodeling in MASLD

Michele Visentin, Zhibo Gai, Anna Kovilakath, Francesca De Luca, Grigorios Panteloglou, Alaa Othman, Mingxia Liu, Francesca Barone, Imme Garrelfs, Joanne Verheij, Belle Vivica van Rosmalen, Ting Gui, Bin Yan, Zhiyong Zhang, Andreas J. Hülsmeier, , Museer A. Lone

This study identifies SPTLC3's role in integrating bile acid-FXR signaling with sphingolipid remodeling in MASLD, showing its dysregulation in human liver and association with disease.

bioRxiv · Aug 25, 2025 · PreprintBiochemistry

The Bardet-Biedl protein Bbs1 controls photoreceptor outer segment protein and lipid composition

Markus Masek, Christelle Etard, Claudia Hofmann, Andreas J. Hülsmeier, Jingjing Zang, Masanari Takamiya, Matthias Gesemann, Stephan C. F. Neuhauss, Thorsten Hornemann, Uwe Strähle, Ruxandra Bachmann‐Gagescu

This study shows that Bbs1 is essential for maintaining photoreceptor outer segment lipid composition and function, with loss leading to early visual deficits and retinal degeneration.

Nature Communications · Mar 11, 2022Peer-reviewedMolecular Biology