ImmunologybioRxivPreprint
IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.
Alicia Derrac Soria, Myles Lewis, Xiao Liu…·Simon A. Jones
The paper identifies CRTAM-expressing CD4+ T-cells in lymphoid-driven synovitis and shows that IL-6 and IL-27 inhibit their activation through STAT3 and ZEB1.