Author

Hans‐Peter Kiem

Fred Hutch Cancer CenterORCID 0000-0001-5949-4947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Keith R. JeromeiD· 2 shared Ailyn Perez· 1 shared Alexis Georgiades· 1 shared Ali Toghani· 1 shared Amogh Pradeep· 1 shared Antonio ScialdoneiD· 1 shared Atsushi KumanogohiD· 1 shared Berthold GöttgensiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

Keith R. JeromeORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 5, 2025

Pooled CAR-T screening in nonhuman primates identifies designs with enhanced proliferation, trafficking, and persistence

Lucy H. Maynard, Eric J. Cavanaugh, Haiying Zhu…·Christopher W. Peterson

This study screens CAR-T designs in nonhuman primates and identifies MyD88-CD40 costimulatory domains as superior for proliferation, trafficking, and persistence.

1 citation

non-human primateexperimental assay

𝕏 PostBluesky

Cell BiologyNature AgingPeer-reviewedJan 29, 2025

Semaphorin 4A maintains functional diversity of the hematopoietic stem cell pool

Dorsa Toghani, Sanika Gupte, Sharon Zeng…·Lev Silberstein

This study identifies Sema4A as an extrinsic factor that protects myeloid-biased HSCs from inflammatory stress, preserving functional diversity in the hematopoietic stem cell pool.

9 citationstop 3%

mousebulk RNA-seq

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GenomicsbioRxivPreprintOct 31, 2021

Host Variation in Type I Interferon Signaling Genes (MX1), CCR5{triangleup}32, and MHC Class I Alleles in Treated HIV+ Non-Controllers Predict Viral Reservoir Size

David A. Siegel, Cassandra Thanh, Eunice Wan…·Sulggi A. Lee

The paper investigates host genetic variations in MX1, CCR5Δ32, and MHC class I alleles in HIV+ non-controllers on ART and finds associations with HIV reservoir size.

2 citations

humanwhole-exome sequencing

𝕏 PostBluesky