David Vauzour

This study shows p-cresol sulfate impairs the blood-brain barrier via EGFR activation and demonstrates EGFR blockade prevents this damage in vitro.

This study shows that TMAO enhances BBB integrity and protects against inflammation, while TMA impairs BBB function and cognitive resilience in mice.

This study shows that FMT from aged mice impairs spatial learning in young recipients by altering hippocampal proteins related to synaptic plasticity and neurotransmission.

This study investigates the association between APOE genotype and gut microbiome composition in humans and APOE-TR mice, finding specific microbial and metabolic differences linked to APOE alleles.