Author

Mikhail Nikolaev

École Polytechnique Fédérale de LausanneORCID 0000-0001-5955-900XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:organoid / primary culture· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Matthias P. LütolfiD· 3 shared Nikolche GjorevskiiD· 2 shared Adrian M. Filip· 1 shared Adrian WolnyiD· 1 shared Alexander van OudenaardeniD· 1 shared Angélique Augustin· 1 shared Anna ErzbergeriD· 1 shared Anna KreshukiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioengineering

Matthias P. LütolfORCID

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3 papers

Recent·Most cited

BioengineeringNature CommunicationsPeer-reviewedFeb 3, 2026

A bioengineered human urothelial organoid model reveals the urine-urothelium interplay in tissue resilience and UPEC recurrence in urinary tract infections

Gauri Paduthol, Mikhail Nikolaev, Kunal Sharma…·John D. McKinney

The paper develops a human urothelial organoid model to study urine-urothelium interactions in UTI resilience and UPEC recurrence, finding that high-solute urine weakens tissue and promotes CWD UPEC formation.

6 citationstop 1%

humanorganoid / primary culture

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BioengineeringbioRxivPreprintMay 2, 2025

Modeling host-microbe interactions in immunocompetent engineered human gut tissues

Rubén López-Sandoval, Marius F. Harter, Qianhui Yu…·J. Gray Camp

The paper develops engineered human gut tissues to study host-microbe interactions and identifies an epithelial gene regulatory network in response to Salmonella Typhimurium infection.

5 citations

humanorganoid / primary culture

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Developmental BiologyThe EMBO JournalPeer-reviewedJul 31, 2023

COORDINATION BETWEEN EMBRYO GROWTH AND TROPHOBLAST MIGRATION UPON IMPLANTATION DELINEATES MOUSE EMBRYOGENESIS

Vladyslav Bondarenko, Mikhail Nikolaev, Dimitri Kromm…·Takashi Hiiragi

This study develops an engineered uterus-like microenvironment to study mouse embryo implantation, revealing coordination between trophoblast migration and embryo growth.

55 citationstop 3%

mouseexperimental assay

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