Author
Fred Hutch Cancer CenterORCID 0000-0001-5962-5441Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Elijah F. Lyons, Lou Devanneaux, Ryan Yue Muller…·Liana F. Lareau
The paper shows that slow translation elongation reduces protein output per mRNA, independent of mRNA stability, and demonstrates a dynamic balance between initiation and elongation rates.
Mary C. Rominger, Siobhan O’Brien, Saksham Gupta…·Alice H. Berger
This paper develops a mouse model of RIT1M90I-driven lung cancer and identifies YAP/TEAD as a therapeutic target for RIT1-mutant lung cancer.
Alexis M. Thornton, Lishan Fang, April Lo…·Angela Norie Brooks
The paper introduces eVIP2, a tool to predict the functional impact of gene variants using gene expression data, and validates its predictions with experimental assays.