Anna V. Freitas

The paper shows that under metabolic stress, many mRNAs lack cap methylation, yet they are still functional, suggesting cap methylation is a stress-responsive regulatory layer.

The paper shows that slow translation elongation reduces protein output per mRNA, independent of mRNA stability, and demonstrates a dynamic balance between initiation and elongation rates.

The paper identifies a transcriptional network regulating mitochondrial biogenesis in Drosophila by combining RNAi screening and ChIP-seq analysis, revealing key factors like CG1603 and YL-1.

The paper generates a high-confidence mitochondrial protein compendium in Dictyostelium discoideum using proteomic and computational methods, identifying 1082 proteins and highlighting unique features compared to other organisms.