Author

Yufan Zhou

The University of Texas at San Antonio Health Science CenterORCID 0000-0002-8385-433XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Reuben S. HarrisiD· 3 shared Benjamin Troness· 2 shared Cameron C. DurfeeiD· 2 shared Harshita B. GuptaiD· 2 shared Joshua ProehliD· 2 shared Nuri A. TemiziD· 2 shared Xingyu LiuiD· 2 shared Allen J. YorkiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCancer Biology

Reuben S. HarrisORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Murine models for triple-negative breast cancer with differential responsiveness to immunotherapy

Thomas J. Kalantzakos, Yufan Zhou, Xingyu Liu, Joshua Proehl, Cameron C. Durfee, Ian M. Tamayo, Nuri A. Temiz, Benjamin Troness, Anusha Soni, Harshita B. Gupta, Reuben S. Harris

The paper develops two murine TNBC models with differing immunotherapy responses for studying treatment mechanisms and therapies.

Journal of Clinical and Translational Science · Apr 1, 2026Peer-reviewedCancer Biology

Faecalibacterium prausnitzii regulates carbohydrate metabolic functions of the gut microbiome in C57BL/6 mice

Peiling Geng, Ni Zhao, Yufan Zhou, Reuben S. Harris, Yong Ge

This study shows that the F. prausnitzii strain UT1 alters gut microbiome composition and carbohydrate metabolism in C57BL/6 mice.

Gut Microbes · Jan 22, 2025Peer-reviewedMicrobiology

Carcinogen-induced DNA adducts amplify APOBEC mutagenesis through nucleotide excision repair

Cameron C. Durfee, Bojana Stefanovska, Rongjie Wu, J. Caballero, Mahmoud A. Ibrahim, Michael A. Carpenter, Liping Liu, Shuvro Prokash Nandi, Prokopios P. Argyris, Luca Boscolo Bielo, Eric C. L. Li, Nuri A. Temiz, Yufan Zhou, Erik N. Bergstrom, Christopher D. Mullally, , Reuben S. Harris

This study shows that carcinogen-induced DNA adducts enhance APOBEC3B-mediated mutagenesis, leading to increased mutation rates in cancer genomes.

bioRxiv · Jan 18, 2025 · PreprintCancer Biology

Integration of scHi-C and scRNA-seq data defines distinct 3D-regulated and biological-context dependent cell subpopulations

Yufan Zhou, Li Tian, Lavanya Choppavarapu, Kun Fang, Shili Lin, Victor X. Jin

The paper integrates scHi-C and scRNA-seq data to identify 3D-regulated cell subpopulations in breast cancer, revealing new chromatin structures and biological contexts.

Nature Communications · Sep 27, 2024Peer-reviewedBioinformatics