Michelle M. Martinez Irizarry

The paper introduces TubuleMAP, a semi-automated 3D tubule tracking pipeline for analyzing tubular networks, achieving high throughput and accuracy in reconstructing kidney and testis tubules.

This study shows IFN-α induces heterogeneous ROS production in human β-cells, with healthier donors having more ROS-accumulating cells, and identifies enriched immune-related genes in ROS-producing cells.

This study shows that deleting megalin in renal proximal tubule cells does not reduce atherosclerosis but causes tubulointerstitial nephritis in male mice fed a Western diet.

This paper shows that deleting Mfn1 and Mfn2 in beta cells impairs mitochondrial structure and insulin secretion, but incretins can partially compensate through EPAC2 signaling.