Author

Santosh Kumar Upadhyay

Institute of Genomics and Integrative BiologyORCID 0000-0001-5999-4351Unclaimed ORCID profile · follow to get notified of new preprints

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Santosh Kumar Upadhyay1 paper · Kumaun University

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Adrian Higginbottom· 1 shared Alexander J. WhitworthiD· 1 shared Álvaro Sánchez-MartíneziD· 1 shared Amy Walton· 1 shared Aytaç GüliD· 1 shared Cameron D. MackerethiD· 1 shared Claire MontmassoniD· 1 shared Claudia S. Bauer· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Adrian Higginbottom

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2 papers

Recent·Most cited

Molecular BiologyScience Translational MedicinePeer-reviewedMar 1, 2023

A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export suppresses neurodegeneration

Lydia M. Castelli, Ya-Hui Lin, Álvaro Sánchez-Martínez…·Guillaume M. Hautbergue

This paper develops a cell-penetrant peptide that blocks C9ORF72-repeat RNA nuclear export, reducing neurodegeneration in preclinical models of ALS and FTD.

16 citations

humanDrosophila

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Molecular BiologyNucleic Acids ResearchPeer-reviewedMar 7, 2020

Structural basis of UCUU RNA motif recognition by splicing factor RBM20

Santosh Kumar Upadhyay, Cameron D. Mackereth

This paper determines the structure of the RBM20 RRM domain bound to UCUU RNA, revealing a coupled folding-binding mechanism for motif recognition.

26 citations

mouseexperimental assay

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