Michelle A. Linterman

This study investigates ZFP36L1's role in Tfh cell differentiation and function, finding that its deletion does not impair GC response or affinity maturation.

This study shows that aged mice have reduced accumulation of small antigens in B cell follicles, potentially affecting vaccine responses.

This study identifies ZFP36L1 and ZFP36L2 as RNA-binding proteins that regulate the G2-M checkpoint in GC B cells to prevent replication stress and maintain genome stability.

The paper shows that mucosal B cell memory selection diverges between lungs and gut, favoring MBCs and PCs respectively, driven by tissue-specific BCR isotype usage rather than affinity.