Author

Alexandra Ciuciu

Thomas Jefferson UniversityORCID 0000-0001-6047-6332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Ryan E. TomlinsoniD· 2 shared Adriana Ciuciu· 1 shared Ashkan SedighiD· 1 shared David Shelton· 1 shared Eric McLaughlin· 1 shared Ibtesam RajpariD· 1 shared John A. Collins· 1 shared Kathryn E. GroppiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

Ryan E. TomlinsonORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 20, 2025

COX2-independent and COX2-dependent effects of naproxen on bone quality, osteocytes, and fatigue fracture healing in male and female mice

Alexandra Ciuciu, Eric McLaughlin, Adriana Ciuciu…·Ryan E. Tomlinson

This study investigates naproxen's effects on bone quality and healing in mice, finding both COX2-dependent and -independent mechanisms with sexual dimorphism.

DOI 10.1101/2025.08.20.669939

mouseimaging

𝕏 PostBluesky

BioengineeringBonePeer-reviewedMay 23, 2025

The Effect of Celecoxib and muMab911 on Strain Adaptive Bone Remodeling and Fracture Repair in Female Mice: Implications for Rapidly Progressive Osteoarthritis

Nicholas J. Ruggiero, Alexandra Ciuciu, Ashkan Sedigh…·Ryan E. Tomlinson

This study examines the effects of celecoxib and muMab911 on bone remodeling and fracture repair in mice, finding they suppress NGF expression and load-induced bone formation, potentially contributing to rapid osteoarthritis progression.

4 citations

mousebulk RNA-seq

𝕏 PostBluesky