Author

Arin K. Oestreich

Washington University in St. LouisORCID 0000-0001-6079-6715Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Farshid GuilakiD· 3 shared Bethany A. AndokoiD· 2 shared Bo ZhangiD· 2 shared Hope D. WelhaveniD· 2 shared Joseph B. LesnakiD· 2 shared Kelle H. MoleyiD· 2 shared Kelsey H. CollinsiD· 2 shared Kristin L. LenziD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPhysiology

Farshid GuilakORCID

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4 papers

Recent·Most cited

PhysiologyOsteoarthritis and CartilagePeer-reviewedOct 1, 2026

Leptin Drives Osteoarthritis Pain Through Sensory Neuron Reprogramming Independent of Cartilage Signaling

Hope D. Welhaven, Elise K Truchan, Kristin L. Lenz…·Kelsey H. Collins

This study shows leptin drives OA pain via sensory neuron reprogramming, not cartilage signaling, by analyzing mouse models and human datasets.

DOI 10.1016/j.joca.2026.10.014

mousebulk RNA-seq

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PhysiologybioRxivPreprintMar 21, 2026

Adipose-driven complement-lipid reprogramming controls nociceptive vulnerability in obesity-associated osteoarthritis

Hope D. Welhaven, Joseph B. Lesnak, Kristin L. Lenz…·Kelsey H. Collins

The paper identifies an adipose-complement-lipid axis that systemically regulates sensory neuron sensitization, explaining pain-structure discordance in obesity-associated osteoarthritis.

1 citation

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Developmental BiologybioRxivPreprintJul 6, 2025

Maternal high-fat/high-sugar diet has short-term dental effects and long-term sex-specific skeletal effects on adult offspring mice

Mohamed G. Hassan, Kyle Hatley Koester, Natalia S. Harasymowicz…·Erica L. Scheller

This study shows that maternal high-fat/high-sugar diet affects craniofacial and dental morphology in adult offspring mice, with sex-specific and generation-persistent skeletal effects in females.

DOI 10.1101/2025.07.06.663396

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Developmental BiologyeLifePeer-reviewedMar 18, 2025

The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy

Pooja Popli, Arin K. Oestreich, Vineet Kumar Maurya…·Ramakrishna Kommagani

This study identifies ATG14's role in preventing unscheduled pyroptosis in the oviduct, ensuring proper embryo transport during early pregnancy.

DOI 10.7554/elife.97325.4

mouseexperimental assay

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