Author

Natalia S. Harasymowicz

Washington University in St. LouisORCID 0000-0002-2140-4157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Farshid GuilakiD· 3 shared Alireza SavadipouriD· 1 shared Alison K. RossiD· 1 shared Arin K. OestreichiD· 1 shared Chia‐Lung WuiD· 1 shared Christine T. N. PhamiD· 1 shared Erica L. SchelleriD· 1 shared Franklin T. MoutosiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersDevelopmental Biology

Farshid GuilakORCID

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3 papers

Recent·Most cited

Maternal high-fat/high-sugar diet has short-term dental effects and long-term sex-specific skeletal effects on adult offspring mice

Mohamed G. Hassan, Kyle Hatley Koester, Natalia S. Harasymowicz, Arin K. Oestreich, Kelle H. Moley, Farshid Guilak, Erica L. Scheller

This study shows that maternal high-fat/high-sugar diet affects craniofacial and dental morphology in adult offspring mice, with sex-specific and generation-persistent skeletal effects in females.

bioRxiv · Jul 6, 2025 · PreprintDevelopmental Biology

PIEZO1-Mediated Mechanotransduction Regulates Collagen Synthesis on Nanostructured 2D and 3D Models of Fibrosis

Neda Rashidi, Natalia S. Harasymowicz, Alireza Savadipour, Nancy S. Steward, Ruhang Tang, Sara J. Oswald, Farshid Guilak

This study shows PIEZO1 regulates collagen synthesis in hASCs based on substrate architecture, with YAP/TAZ translocation and collagen production being independent outcomes of PIEZO1 activation.

Acta Biomaterialia · Dec 13, 2024Peer-reviewedBioengineering

A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery

Yun‐Rak Choi, Kelsey H. Collins, Luke E. Springer, Lara Pferdehirt, Alison K. Ross, Chia‐Lung Wu, Franklin T. Moutos, Natalia S. Harasymowicz, Jonathan M. Brunger, Christine T. N. Pham, Farshid Guilak

This paper develops a bioartificial implant using CRISPR-Cas9-engineered stem cells to deliver anti-cytokine drugs in response to inflammation, reducing arthritis severity in mice.

Science Advances · Sep 3, 2021Peer-reviewedSynthetic Biology