Author

Youssef M. Zohdy

Emory UniversityORCID 0000-0001-6089-4833Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Abdelhameed S. Dawood· 2 shared Ahmet OzdilekiD· 2 shared Mohamed S. Abdel-HakeemiD· 2 shared Ahmed Mahgoub· 1 shared Akil AkhtariD· 1 shared Alexandra S. FlegleiD· 1 shared Arman JahangiriiD· 1 shared Autumn A. Gavora· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Abdelhameed S. Dawood

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3 papers

Recent·Most cited

Preexisting chronic infection skews the epigenetic landscape of subsequent memory CD8 T cell responses

Abdelhameed S. Dawood, Elizabeth E. Wolfson, Silmi Jiwani, Ahmet Ozdilek, Youssef M. Zohdy, Tylisha Gourdine, Sheikh Abdul Rahman, Jeffrey Alan Tomalka, Mohamed S. Abdel-Hakeem

The paper shows that preexisting chronic LCMV infection skews the epigenetic and phenotypic responses of subsequent memory CD8 T cells to Listeria infection.

bioRxiv · Apr 29, 2026 · PreprintImmunology

Longitudinal multi-omics reveals pathogenic TSC2 variants disrupt developmental trajectories of human cortical organoids derived from Tuberous Sclerosis Complex

Weibo Niu, Shaojun Yu, Xiangru Li, Zhen Wang, Rui Chen, Christina Michalski, Arman Jahangiri, Youssef M. Zohdy, Joshua J. Chern, Ted J. Whitworth, Jianjun Wang, Jie Xu, Ying Zhou, Zhaohui Steve Qin, Bingshan Li, , Zhexing Wen

This study uses longitudinal multi-omics analysis of cortical organoids to show that TSC2 pathogenic variants disrupt neurodevelopmental trajectories, leading to synaptic and mitochondrial dysfunction.

bioRxiv · Oct 7, 2024 · PreprintNeuroscience

Longitudinal Proteomic Profiling of T Cell Differentiation In Vivo Reveals Biochemical Remodeling Underlying Exhaustion

Christian Michel Beusch, Abdelhameed S. Dawood, Ahmet Ozdilek, Sarah Welbourn, Youssef M. Zohdy, Christopher M. Monaco, Alexandra S. Flegle, Ahmed Mahgoub, Sakshi Malik, Christina Niavi, Akil Akhtar, Carly J. Roman, Autumn A. Gavora, David Ezra Gordon, Mohamed S. Abdel-Hakeem

This study profiles longitudinal proteomic and phosphoproteomic changes in CD8 T cells during acute and chronic infections, identifying exhaustion-associated proteins and phosphosites with potential therapeutic relevance.

bioRxiv · May 14, 2024 · PreprintImmunology