Jie Xu

Baseline growth rate shapes pollutant impacts in aquatic environments: Evidence from antibiotic responses in the harmful cyanobacterium Microcystis

This study shows that baseline growth rate in Microcystis affects antibiotic-induced hormetic responses, with slow-growing populations showing greater growth enhancement at low antibiotic concentrations.

Rac1 and CHK1 Converge on Abi-1 to Regulate DNA Repair Dependency and Treatment Response in Human Cancers

This study identifies Abi-1-S323 phosphorylation as a biomarker for DNA repair states and treatment response in cancers, showing its role in regulating radiosensitivity through Rac1 and CHK1 signaling.

GIN-CRC-Pareto: A graph-based Pareto-optimal multi-task learning framework to identify miRNA-target interactions in colorectal cancer

GIN-CRC-Pareto identifies miRNA-target interactions in colorectal cancer using a graph-based multi-task learning framework, outperforming existing methods in accuracy and AUC.

Longitudinal multi-omics reveals pathogenic TSC2 variants disrupt developmental trajectories of human cortical organoids derived from Tuberous Sclerosis Complex

This study uses longitudinal multi-omics analysis of cortical organoids to show that TSC2 pathogenic variants disrupt neurodevelopmental trajectories, leading to synaptic and mitochondrial dysfunction.

Outer Membrane Vesicle Mediated Multidrug Resistance Gene Transfer in Avibacterium Paragallinarum

This study compares the genomic characteristics of outer membrane vesicles (OMVs) from Avibacterium paragallinarum with its parent strain and shows that OMVs can temporarily transfer antibiotic resistance genes.

An Integrated Framework for Genome Analysis Reveals Numerous Previously Unrecognizable Structural Variants in Leukemia Patients' Samples

The paper identifies numerous previously undetected structural variants in leukemia samples using integrated genome analysis and computational methods, revealing their impact on gene expression and patient survival.

Increased green autofluorescence is a marker for non-invasive prediction of H2O2-induced cell death and decreases in the intracellular ATP of HaCaT cells

Metabolomics and proteomics analyses of grain yield reduction in rice under abrupt drought-flood alternation

This study identifies differential metabolites and proteins in rice under abrupt drought-flood alternation, revealing key metabolic and stress response pathways during panicle differentiation.