Sirena Soriano

Sex-specific effects of fecal microbiota transplantation on TBI-exacerbated Alzheimer's pathology in mice

This study investigates how fecal microbiota transplantation (FMT) affects Alzheimer's pathology and neuroinflammation in male and female mice with traumatic brain injury, finding sex-specific outcomes.

Antibiotic-induced changes to the gut microbiome attenuate neuroinflammation in a mouse model of TBI

This study shows that antibiotic treatment reduces neuroinflammation and neurodegeneration after TBI in mice by altering the gut microbiome.

Probiotic treatment causes sex-specific neuroprotection after traumatic brain injury in mice

This study shows that probiotic treatment reduces TBI severity and behavioral deficits in male mice but not female mice.

Sex-dependent improvement in traumatic brain injury outcomes after liposomal delivery of dexamethasone in mice.

This study shows that liposomal dexamethasone reduces TBI lesion volume and inflammation in male mice but not females.

Counter-balancing X-linked Mecp2 hypofunction by hyperfunction ameliorates disease features in a model of Rett syndrome: implications for genetic therapies

In a mouse model of Rett syndrome, counterbalancing mosaic LOF with complementary mosaic GOF improves phenotypic outcome.

Fecal microbiota transplantation derived from Alzheimer's disease mice worsens brain trauma outcomes in wild-type controls

This study shows that fecal microbiota from Alzheimer's mice worsens brain injury outcomes in healthy mice.

Emu: Species-Level Microbial Community Profiling for Full-Length Nanopore 16S Reads

Emu provides species-level microbial community profiling using full-length 16S rRNA reads with improved accuracy over existing methods.