Intracellular lipopolysaccharide binds RETREG1/FAM134B to regulate ER remodeling upon bacterial infection
Yi‐Lin Cheng, João Mello-Vieira, Adriana Covarrubias‐Pinto, Alexis González, Santosh Kumar Kuncha, Chun Kew, K. Zhang, Muhammad Awais Afzal, Nour Diab, Sophia Borchert, Siou-Ying Hong, Timothy Chun Huang, Wenbo Chen, Uxía Gestal Mato, Mathias Walter Hornef, , Ivan Đikić
This study shows that bacterial LPS binds RETREG1 to induce ER remodeling and enhance antibacterial defense through ERphagy.
Autophagy · May 12, 2026Peer-reviewedCell Biology