João Mello-Vieira

This study shows that bacterial LPS binds RETREG1 to induce ER remodeling and enhance antibacterial defense through ERphagy.

This study shows MTMR14 is recruited to damaged lysosomes to remodel lipids, reduce mTORC1 signaling, and support proteostasis during lysosomal injury.

This study identifies that phosphoribosyl ubiquitination of SNARE proteins STX17 and SNAP29 by Legionella SidE effectors regulates autophagy hijacking during infection.