Author

Vandana Malhotra

University of DelhiORCID 0000-0001-6138-1909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhishek Dinkarnath GargiD· 2 shared Abhishek GargiD· 1 shared Abhishek HalderiD· 1 shared Amita Gupta· 1 shared Arjun RayiD· 1 shared Bernadette MathewiD· 1 shared Debarka SenguptaiD· 1 shared Debjit Pramanik· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersEvolutionary Biology

Abhishek Dinkarnath GargORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Evolutionary BiologyiSciencePeer-reviewedNov 1, 2026

Intra-DNA k-mer Conservation Patterns Encode Evolutionary Selection of Variants

Bernadette Mathew, Abhishek Halder, Nancy Jaiswal…·Debarka Sengupta

The paper introduces kGain, a metric quantifying k-mer frequency shifts due to mutations, and shows it predicts adaptive potential across species and experimental systems.

DOI 10.1016/j.isci.2026.118142

E. colimouse

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BiochemistrymBioPeer-reviewedJun 17, 2025

Ser/Thr Phosphorylation of Mycobacterium tuberculosis Type II Rel TA module by Protein Kinase K interferes with toxin neutralization: A novel mode of TA regulation.

Shafinaz Rahman Sarah, Abhishek Garg, Sadiyah Afroz…·Vandana Malhotra

This study identifies Ser/Thr phosphorylation by PknK as a novel regulatory mechanism for Type II TA modules in M. tuberculosis, disrupting toxin-antitoxin interactions.

2 citations

proteomicsstatistical model

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BiochemistrybioRxivPreprintDec 19, 2023

Anti-cancer drug Tamoxifen interferes with Mycobacterium tuberculosis PhoPR mediated signaling and inhibits mycobacterial growth

Abhishek Dinkarnath Garg, Mansi Pandit, Vandana Malhotra, Deepak Kumar Saini

This study identifies Tamoxifen as an inhibitor of Mycobacterium tuberculosis PhoPR signaling, reducing bacterial growth and disrupting downstream gene expression.

DOI 10.1101/2023.12.19.571805

experimental assayhost-pathogen & immune response

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