Abhishek Dinkarnath Garg

Intra-DNA k-mer Conservation Patterns Encode Evolutionary Selection of Variants

The paper introduces kGain, a metric quantifying k-mer frequency shifts due to mutations, and shows it predicts adaptive potential across species and experimental systems.

Distinct tumor immune microenvironmental (TIME) landscapes drive divergent immunotherapy responses in glioblastoma

This study identifies three distinct tumor immune microenvironment (TIME) subtypes in glioblastoma (GBM) with divergent responses to immunotherapy, supporting personalized treatment strategies.

The molecular landscape of polycystic kidneys is marked by common alterations in purine metabolism

The paper identifies purine metabolism as a common altered pathway in ADPKD cysts and cell models, showing its modulation suppresses cyst formation in vitro.