Author

Paula R. Haynes

Howard Hughes Medical InstituteORCID 0000-0001-6223-8581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 3 Assay:metabolomics· 2 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

Amita SehgaliD· 4 shared Aalim M. WeljieiD· 2 shared Arjun SenguptaiD· 2 shared Dania M. MalikiD· 2 shared Shirley ZhangiD· 2 shared Zhifeng Yue· 2 shared Allan I PackiD· 1 shared Andrew D. Nguyen· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersBiochemistry

Amita SehgalORCID

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4 papers

Recent·Most cited

BiochemistryeLifePeer-reviewedSep 24, 2026

Integrated Respirometry and Metabolomics Unveil Circadian Metabolic Dynamics in Drosophila

Farheen Akhtar, Dania M. Malik, Arjun Sengupta…·Aalim M. Weljie

This study combines respirometry and metabolomics to analyze circadian metabolic dynamics in Drosophila, showing how sleep and circadian disruptions affect metabolic rates and redox homeostasis.

DOI 10.7554/elife.108681.3

Drosophilametabolomics

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NeurosciencebioRxivPreprintSep 10, 2025

Neutral lipid processing in glia is sexually dimorphic and promotes sleep through diacylglycerol catabolism

Elana S. Pyfrom, Connor H. Beveridge, Paula R. Haynes…·Amita Sehgal

The paper identifies sex-specific lipid differences in Drosophila neurons and glia and links glial diacylglycerol catabolism to sleep promotion.

2 citations

Drosophilastatistical model

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Systems BiologybioRxivPreprintOct 30, 2023

Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis over a day:night cycle

Dania M. Malik, Seth D. Rhoades, Shirley Zhang…·Aalim M. Weljie

This study uses isotope tracing to show rhythmic glucose metabolism in Drosophila, revealing internal mechanisms controlling metabolic homeostasis across day and night.

2 citations

Drosophilametabolomics

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GeneticseLifePeer-reviewedJan 31, 2023

Ecdysone acts through cortex glia to regulate sleep in Drosophila

Yongjun Li, Paula R. Haynes, Shirley Zhang…·Amita Sehgal

This study shows ecdysone acts through cortex glia to regulate sleep in Drosophila by modulating lipid metabolism.

34 citationstop 5%

Drosophilaexperimental assay

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