Shirley Zhang

Arsenic impairs Drosophila neural stem cell mitotic progression and sleep behavior in a tauopathy model

This study shows arsenic exposure impairs Drosophila neural stem cell mitosis and adult sleep behavior, linking it to neurotoxicity and tauopathy.

Modulation of RNA processing genes during sleep-dependent memory

The paper identifies RNA processing genes modulated during sleep-dependent memory in Drosophila and shows their effects on sleep and memory consolidation.

Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms

This study shows that age-related blood-borne factors alter circadian gene expression in cultured fibroblasts, affecting oxidative phosphorylation and cholesterol biosynthesis pathways.

Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis over a day:night cycle

This study uses isotope tracing to show rhythmic glucose metabolism in Drosophila, revealing internal mechanisms controlling metabolic homeostasis across day and night.

Ecdysone acts through cortex glia to regulate sleep in Drosophila

This study shows ecdysone acts through cortex glia to regulate sleep in Drosophila by modulating lipid metabolism.

A circadian clock in the blood-brain barrier regulates xenobiotic efflux from the brain

The paper shows that the Drosophila blood-brain barrier has a circadian permeability rhythm driven by a clock in perineurial glia, with nighttime increased permeability enhancing drug efficacy.