Author

Elana S. Pyfrom

University of PennsylvaniaORCID 0000-0002-1875-1289Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:Drosophila· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Amita SehgaliD· 2 shared Samantha L. Killiany· 2 shared Zhifeng Yue· 2 shared Caitlin E. RandolphiD· 1 shared Camilo GuevaraiD· 1 shared Connor H. Beveridge· 1 shared Erick Astacio· 1 shared Gaurav ChopraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Amita SehgalORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Sleep controls peroxisomal abundance to reduce wake-induced brain oxidation

Camilo Guevara, Yongjun Li, Elana S. Pyfrom, Samantha L. Killiany, Zhifeng Yue, Amita Sehgal

This study shows that sleep regulates peroxisomal abundance to reduce brain oxidation caused by wakefulness, with Pex16 playing a key role in sleep regulation and lipid metabolism.

bioRxiv · Nov 28, 2025 · PreprintNeuroscience

Neutral lipid processing in glia is sexually dimorphic and promotes sleep through diacylglycerol catabolism

Elana S. Pyfrom, Connor H. Beveridge, Paula R. Haynes, Vishal A. Kanigicherla, Caitlin E. Randolph, Paula Carvalho Costa, Seble G. Negatu, Sanjay N. Iyer, Samantha L. Killiany, Zhifeng Yue, Erick Astacio, Katherine A. Walker, Kiet N. Luu, Pavel Pivarshev, Kellie A. Jurado, , Amita Sehgal

The paper identifies sex-specific lipid differences in Drosophila neurons and glia and links glial diacylglycerol catabolism to sleep promotion.

bioRxiv · Sep 10, 2025 · PreprintNeuroscience