Author

Susan Schlenner

KU LeuvenORCID 0000-0002-8553-3388Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Açelya YilmazeriD· 1 shared Ana Escribano· 1 shared Ana Victoria Rojo‐GarcíaiD· 1 shared Andreas DahliD· 1 shared Andreas PetzoldiD· 1 shared Anne EugsteriD· 1 shared Antonios ChatzigeorgiouiD· 1 shared Astrid De RooveriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Açelya YilmazerORCID

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3 papers

Recent·Most cited

FERMT2 expression in human articular chondrocytes is regulated by hypoxia-associated transcriptional programs

Ana Victoria Rojo‐García, Astrid De Roover, Ana Escribano, Susan Schlenner, Silvia Monteagudo, Rik Jozef Urbain Lories

This study identifies hypoxia as a regulator of FERMT2 expression in human chondrocytes, showing it enhances FERMT2 without adverse effects on ECM, while other factors like GATA1 and MEF2A also influence its expression.

bioRxiv · Sep 11, 2026 · PreprintMolecular Biology

The quest continues: Human CD4+ CD16+ CD56+ "exTreg" resemble NKT cells instead

Jeevan Mutha, Meghana Konga, Maximilian Sprang, Johannes U. Mayer, Susan Schlenner

The paper re-evaluates the identity of CD4+ CD56+ CD16+ cells in human PBMC, finding they resemble NKT cells rather than exTreg, and explores Treg stability and Tr17 induction for therapeutic applications.

bioRxiv · Aug 5, 2025 · PreprintImmunology

Functional Dichotomy of Developmental Foxp3+ Treg Cell Subsets in the Visceral Adipose Tissue of Lean and Obese Mice

Açelya Yilmazer, Anne Eugster, Dimitra Maria Zevla, Sara Salome Helbich, Marie Boernert, Basak Torun, Elda Marsela, Emre Kirgin, Andreas Dahl, Andreas Petzold, Olivia Kershaw, Vasileia Ismini Alexaki, Antonios Chatzigeorgiou, Michael Delacher, Susan Schlenner, Karsten Kretschmer

This study investigates the functional differences between thymic and peripheral Treg cells in visceral adipose tissue, showing that tTreg instability contributes to inflammation and obesity while pTreg cells protect against metabolic disorders.

bioRxiv · Mar 12, 2025 · PreprintImmunology