Florent Di Meo

This paper reveals that tacrolimus inhibits C. glabrata Cdr1 by stabilizing its inward-facing conformation, blocking ATP hydrolysis and azole transport.

This study develops a proximal tubule-on-chip model to investigate dynamic drug transporter expression and function, showing flow exposure modulates mRNA expression and enhances cell polarization.

This study uses molecular dynamics simulations to investigate ABCB4 transport mechanisms, revealing membrane-dependent dynamics and dual translocation pathways for phosphatidylcholine.