Author

Theo Benefice

Lyon 1 Université

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Organism:yeast· 1

Frequent Co-Authors

Ahcène BoumendjeliD· 1 shared Eleftherios ZarkadasiD· 1 shared Erwin LampingiD· 1 shared Florent Di MeoiD· 1 shared Guy SchoehniD· 1 shared Jorgaq PataiD· 1 shared Nour Samrouth· 1 shared Pierre FalsoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ahcène BoumendjelORCID

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1 paper

Recent·Most cited

The immunosuppressant tacrolimus (FK506) inhibits C. glabrata Cdr1 efflux pump function by stabilizing the inward-facing conformation.

Rim Baccouch, Theo Benefice, Eleftherios Zarkadas, Nour Samrouth, Jorgaq Pata, Sandrine Magnard, Florent Di Meo, Raphaël Terreux, Stephanie Aguero, Ahcène Boumendjel, Guy Schoehn, Erwin Lamping, Pierre Falson, Vincent Chaptal

This paper reveals that tacrolimus inhibits C. glabrata Cdr1 by stabilizing its inward-facing conformation, blocking ATP hydrolysis and azole transport.

bioRxiv · Jul 8, 2026 · PreprintBiochemistry