Fission yeast Fss1, a PQ-loop membrane protein, acts in diploids to build full-thickness, chitin-containing spore walls and within spores to maintain vacuole morphology and timely germination.

bioRxiv · Oct 31, 2026 · PreprintGenetics✦ In-depth digest

A tool to dissect heterotypic determinants of homotypic protein phase behavior

Hannah Kimbrough, Jacob Jensen, Caleb Weber, Tayla Miller, Lucinda E. Maddera, Jillian F Blanck, Vignesh M. P. Babu, William B. Redwine, Randal Halfmann

The paper introduces a tool to study how modifier proteins affect the phase behavior of query proteins through controlled interaction modulation.

Protein Science · Jun 16, 2025Peer-reviewedBiophysics

Long-term hybridization in a karst window reveals the genetic basis of eye loss in cavefish

Riley Kellermeyer, Luis Espinasa, Chris Seidel, William B. Redwine, Rachel L. Moran, Sylvain Bertho, Emma Y. Roback, Claudia Patricia Ornelas-García, Dana Alegre, Kyle Weaver, Jay Unruh, Benjamin Troutwine, Yongfu Wang, Tathagata Biswas, Masato Yoshizawa, , Nicolas Rohner

The paper identifies a specific SNP in Cx50 linked to eye loss in cavefish using a hybrid population from a karst window.

bioRxiv · Oct 25, 2024 · PreprintEvolutionary Biology