Chris W. Seidel

This study identifies a naturally evolved mutation in mc3r that alters energy homeostasis across development in cavefish, contributing to adaptation to nutrient scarcity.

This study shows that loss of polr1c in zebrafish causes reduced myelination and craniofacial defects, with Tp53 pathway activation but no apoptosis in oligodendrocyte precursors.

This study identifies a centralized oral nerve ring in Nematostella vectensis with molecular and functional features similar to bilaterian interneurons, suggesting neural centralization predates the cnidarian-bilaterian split.

This study identifies NR6A1 as a critical regulator of mammalian neural crest cell specification, formation, and survival through loss-of-function experiments and multiomic analyses.

This study assembles human Robertsonian chromosomes, identifies a common breakpoint and centromere epigenetic changes, and explores structural features enabling their formation.

The paper identifies a specific SNP in Cx50 linked to eye loss in cavefish using a hybrid population from a karst window.

This study identifies Hox gene functions in adult tissue segmentation and asexual reproduction in planarians, showing distinct roles for hox3 and post2b.

The paper investigates how wtf4 meiotic drivers in S. pombe use dual transcriptional regulation and selective protein exclusion to ensure their transmission through gametes.

The paper identifies Nord as a Dpp/BMP feedback regulator that interacts with Dally to modulate signaling in Drosophila wing development.

The paper identifies cis-regulatory changes in cavefish that contribute to metabolic adaptation by analyzing epigenetic differences between surface and cave populations.

The paper identifies two antimicrobial peptides that regulate long-term memory in Drosophila but not short-term memory or instinctive behavior.

The paper identifies transcriptional regulators of epidermal lineage differentiation in planarians and discovers novel secreted organelles.