Shane P. D’Souza

This study shows melanopsin regulates local axonal translation in developing ipRGCs, affecting circuit assembly and synaptic development before eye-opening.

This study shows that circadian misalignment contributes to myopia across species, with reversible effects in mice and associations in human populations.

The paper introduces an improved Opn4cre mouse line for selectively targeting ipRGCs, showing higher specificity and distinct labeling patterns compared to existing lines.

The paper identifies a retinal signaling pathway where melanopsin-expressing retinal ganglion cells regulate rod photoreceptor number during development through light-dependent communication.

This study shows that dopamine release in the lateral shell of the ventral striatum encodes visual stimulus properties like luminance changes rather than threat level in mice.