Richard A. Lang

The paper investigates UVB-induced calcium signaling in mouse corneal epithelial cells, identifying OPN5 and TRPV4 as key components of an intrinsic photosensitive pathway that triggers cytokine release and inflammatory responses.

The paper introduces an improved Opn4cre mouse line for selectively targeting ipRGCs, showing higher specificity and distinct labeling patterns compared to existing lines.

The paper identifies a retinal signaling pathway where melanopsin-expressing retinal ganglion cells regulate rod photoreceptor number during development through light-dependent communication.

This study shows that dopamine release in the lateral shell of the ventral striatum encodes visual stimulus properties like luminance changes rather than threat level in mice.

This study shows that violet light improves memory and mood in aged mice by activating OPN5-positive retinal ganglion cells and modulating brain regions like the habenula.

This study demonstrates that melanopsin-expressing ganglion cells in fetal mouse retinas are light-responsive and identify the transduction pathways involved.

This study shows that melanopsin and GNAQ signaling in fetal mouse eyes is necessary and sufficient for normal vascular development.

This study identifies a light-OPN3 pathway in adipocytes that regulates circadian rhythms, energy balance, and thermogenesis in mice.