Adele Alagia

The paper reveals the structural basis of hDicer-tRNA complex formation and shows that m5C modification facilitates tRNA cleavage by hDicer.

This study shows NSUN2 facilitates DICER cleavage of DARTs-associated R-loops to promote DNA repair after damage.

This study shows TIRR binds specific mRNAs and interacts with XPO1 and P bodies during DNA damage, aiding mRNA export and DNA repair.

The paper shows that the SOSS1 complex and RNA polymerase II form phase-separated compartments at double-strand breaks to facilitate DNA repair.

The paper shows that svtRNA1-2, a Dicer-dependent small vault RNA, modulates expression of cell membrane proteins by silencing nascent RNA through specific hybridization features.