Author

Kamal Ajit

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:DNA methylation· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Monika GullerováiD· 5 shared Adele AlagiaiD· 2 shared Arianna Di FazioiD· 2 shared Qilin LongiD· 2 shared Abdullah Abdullah· 1 shared Annabelle ShawiD· 1 shared Federica BattistiniiD· 1 shared Felipe BeckedorffiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersMolecular Biology

Monika GullerováORCID

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5 papers

Recent·Most cited

Structural and functional basis of the non-canonical human Dicer-tRNA complex

Arianna Di Fazio, Stephan Hirschi, Federica Battistini, Nuno Santos, James Boot, Kamal Ajit, Abdullah Abdullah, Adele Alagia, Modesto Orozco, Monika Gullerová

The paper reveals the structural basis of hDicer-tRNA complex formation and shows that m5C modification facilitates tRNA cleavage by hDicer.

bioRxiv · Aug 17, 2026 · PreprintMolecular Biology

NSUN2 Facilitates DICER Cleavage of DNA Damage-Associated R-Loops to Promote Repair

Adele Alagia, Kamal Ajit, Arianna Di Fazio, Qilin Long, Monika Gullerová

This study shows NSUN2 facilitates DICER cleavage of DARTs-associated R-loops to promote DNA repair after damage.

Nature Communications · Aug 23, 2025Peer-reviewedMolecular Biology

Tetrameric INTS6-SOSS1 complex facilitates DNA:RNA hybrid autoregulation at double-strand breaks

Qilin Long, Kamal Ajit, Kateřina Šedová, Vojtech Haluza, Richard Štefl, Sadat Dokaneheifard, Felipe Beckedorff, Monica G Valencia, Marek Šebesta, Ramin Shiekhattar, Monika Gullerová

The paper identifies the tetrameric INTS6-SOSS1 complex as essential for DNA:RNA hybrid autoregulation at double-strand breaks, facilitating DNA repair through PP2A recruitment and DARTs prevention.

Nucleic Acids Research · Oct 8, 2024Peer-reviewedMolecular Biology

Y RNA-derived fragments in a complex with YBX1 modulate PARP1 residency at DNA double strand breaks

Annabelle Shaw, Kamal Ajit, Monika Gullerová

The paper shows Y RNA-derived fragments packaged with YBX1 enhance PARP1 residency at DNA double strand breaks, improving DNA repair and cell survival through ADP-ribosylation.

bioRxiv · Jun 18, 2024 · PreprintMolecular Biology

GATAD2B containing NuRD complex drives R-loop dependent chromatin boundary formation at double strand breaks

Zhichao Liu, Kamal Ajit, Yupei Wu, Wei‐Guo Zhu, Monika Gullerová

This study shows the GATAD2B-NuRD complex regulates chromatin boundaries at DSBs by promoting histone deacetylation and condensation, essential for proper DNA repair.

bioRxiv · Feb 19, 2024 · PreprintMolecular Biology