Qingfeng Chen

This study demonstrates the feasibility of using dual-ssAAV6 vectors for in vivo gene delivery to HSC from thalassemia patients in a humanized mouse model, showing efficient transduction and long-term persistence.

This study identifies cortactin's role in suppressing mTOR-dependent senescence in CTCs, leading to metastatic dormancy, and proposes a therapeutic strategy combining cortactin depletion and senolytics.

This study identifies transcriptomic and immune features of gastric cancer peritoneal metastases, highlighting predictive markers and therapeutic targets in the tumor microenvironment.

This study shows that aberrant non-canonical NF-kappaB signalling reprograms the epigenome to drive oncogenic transcriptomes in multiple myeloma by promoting super-enhancers and cis-regulatory interactions.

The paper analyzes the exometabolome of decidualizing human endometrial stromal and perivascular cells to identify differentially secreted metabolites and their metabolic pathways during decidualization.