Olga A. Soutourina

The paper identifies three families of bacterial tRNA-like RNAs through structural and genetic analysis, linking one family to sporulation control in Clostridioides difficile.

This study identifies a family of small proteins regulated by c-di-GMP riboswitches that mediate sporulation in C. difficile, showing their role in spore formation and developmental regulation.

The paper identifies a new AbiF-like system in C. difficile and shows its regulation by a non-coding RNA through RNA-protein interactions.

This study shows that cephalosporin resistance in C. difficile is due to inhibition of D,D-carboxypeptidases, not L,D-transpeptidases, and highlights the plasticity of PG biosynthesis.

This paper uses dual RNA-seq to study coding and non-coding RNA expression dynamics in C. difficile infection in mice, identifying new ncRNA genes and host miRNAs associated with infection.

The paper develops regulatory, metabolic, and integrated models for C. difficile to understand its colonization mechanisms and interactions with the gut microbiota.